You are here

New Article in Scientific American - Is Estrogen Deficiency a Thing?

Is Estrogen Deficiency a Thing?

If yes, it is rare.

Estrogen deficiency is primarily a marketing slogan.

The Centre for Menstrual Cycle and Ovulation Research (CeMCOR, ) today published in Scientific American

This piece questions the current focus on estrogen deficiency.

Estrogen deficiency appears to be very common in adolescents, premenopausal, perimenopausal and menopausal women. Polycystic Ovary Syndrome (PCOS) is described that way because of far apart periods despite its higher estrogen and lower progesterone levels.

This new paper asserts the physiological reality that disturbances of ovulation and lower progesterone levels are the earliest menstrual cycle adaptation. Ovulatory disturbances occur about a third of the time in a single random cycle in a population-based study in Norway (PLOS ONE 2015).

Adaptive changes in ovulatory disturbances commonly occur to social, psychological, nutritional and combined stressors, and rarely lengthen or take away periods and therefore lower estrogen levels.

More information is available at or by asking a question here:

Estrogen’s Storm Season: Stories of Perimenopause

Estrogen's Storm Season

by Dr. Jerilynn C Prior

New second edition available

Estrogen’s Storm Season is now available in BOTH print and eBook (Mobi and ePUB) versions!

All royalties are recieved in our Endowment fund (overseen by UBC) and support CeMCOR's research and future.

It is full of lively, realistic stories with which women can relate and evidence-based, empowering perimenopause information. It was a finalist in 2006 for the Independent Publisher Book Award in Health.

Purchase your ebook copy via our Amazon Kindle or
Google Play storefronts!

Paperback copies (with updated insert) still available here.

Join a Study:

Get Involved

Volunteer research participants are the heart of all CeMCOR research. Participants are invited to provide feedback on study processes, to learn their own results and at the end of a study, be the first to hear what the whole study found. Please become a CeMCOR research participant—you can contribute to improving the scientific information available for daughters, friends and the wider world of women.