Since 1980, Dr. Jerilynn C. Prior and colleagues have been studying women’s
menstrual cycles and ovulation. A focus has been on longitudinal observational
studies analyzing within-woman changes in response to, for example, exercise
training or chemotherapy for breast cancer. Documented changes occur within the
menstrual cycle and ovulation, in physical and emotional experiences and in bone
mineral density and bone metabolism. Another primary focus for research is using
randomized controlled trials to assess the effects of progesterone therapy on
metabolism, endothelial function, hot flushes/night sweats, experiences and bone
changes.
The Centre for Menstrual Cycle and Ovulation Research philosophy is that each
participant becomes part of the research team, is provided her own and
preliminary results and provides feedback on the project. Dr. Prior personally
undergoes all research interventions before they are approved as part of any
research.
The Centre for Menstrual Cycle Research and Ovulation undertakes projects
supported by pharmaceutical companies only if the research is designed,
conducted and analyzed by CeMCOR scientists. It will also not accept support
unless whatever results are discovered can be submitted for publication.
Current Focus
The research focus for CeMCOR is broadening to include the epidemiology of
women’s reproduction. Data from the Canadian Multicentre Osteoporosis Study
relating to women’s reproduction will be examined using both the baseline and
5-yr databases. For background to this analysis, Drs. Jerilynn C. Prior and Siri
Forsmo are completing an exhaustive review of women’s reproductive epidemiology.
CeMCOR previously used measured endpoints like bone change in studies of
menstrual cycles and ovulation. CeMCOR is now focusing more closely on changes
in women’s experiences collected using self-report instruments. The Menstrual
Cycle Diary® database includes cycles collected over one year by more than 60
ovulatory women and by about 30 women with hypothalamic suppression of menstrual
cycles or ovulation.